Moni Toplou (Greek: Μονή Τοπλού) is a 15th-century monastery located in a dry and barren area in the Lasithi regional unit, on the eastern part of the island of Crete in Greece. It is about 6 km north of the village of Palekastro and 85 km east of Agios Nikolaos. The monastery was originally called Panagia Akrotiriani (Virgin Mary of the Cape), after the nearby Sidero cape.