Regina High School was a private, Catholic all-girls high school located in South Euclid, Ohio. It was run by the Sisters of Notre Dame, who also run Notre Dame College, which is located next door. It was a part of the Roman Catholic Diocese of Cleveland. Approximately one fifth of the teachers were nuns; the remaining teachers are both male and female lay persons. The school offered the students the ability to grow in an environment that supports them and encourages them to be who they are. The school announced in October 2009 that the 2009-2010 school year would be its last.