Otterbein is a small neighborhood of historic rowhouses in Baltimore, Maryland, United States. Otterbein is immediately southwest of, and in close walking distance to, the Inner Harbor. The neighborhood is very compact, entirely located between Hanover Street and Sharp Street, and between Barre Street and Henrietta Street. It is in small parts of zip codes 21201 and 21230. This neighborhood is affluent, with some of the highest property values in the city.