Kyles Ford is an unincorporated community in Hancock County in the U.S. state of Tennessee. It is located along the Upper Clinch River and houses the TWRA's Kyles Ford Wildlife Management Area. A portion of Kyles Ford is included an 850-acre (3.4 km²) parcel of land referred to as the Kyles Ford Preserve. The parcel was acquired by TWRA in partnership with The Nature Conservancy and other conservation groups in a combined effort to preserve the area's rare, threatened, and endangered species of freshwater mussels. The concerned area of the Upper Tennessee River watershed that includes the Powell River Tributary, contains the most biologically diverse concentration of freshwater mussels in the Continental United States.