Wheeling is a city in the State of West Virginia and is the county seat of Ohio County, but it also has some subdivisions in Marshall County. Located along the Ohio River in the foothills of the Appalachian Mountains, Wheeling was originally a settlement in the British colony of Virginia and later an important city in the Commonwealth of Virginia. Wheeling was the first state capital of West Virginia. Thanks to its location along major transportation routes, including the Ohio River, National Road, and the B&O Railroad, Wheeling became a manufacturing center in the late nineteenth century.