The Pocomoke River stretches approximately 66 miles (106 km) from southern Delaware through southeastern Maryland in the United States. At its mouth, the river is essentially an arm of Chesapeake Bay, whereas the upper river flows through a series of relatively inaccessible wetlands called the Great Cypress Swamp, largely populated by Loblolly Pine, Red Maple and Bald Cypress. The river is the easternmost river that flows into Chesapeake Bay and is reputed to be one of the deepest rivers for its width in the world.