Arrow Rock is a village in Saline County, Missouri, United States, located near the Missouri River. The village has important historical significance related to westward expansion, the Santa Fe Trail and 19th century artist George Caleb Bingham. The state’s first state historic site is located here and the entire village was designated a National Historic Landmark by the Department of the Interior, National Park Service in 1963. Many structures within the village are also individually listed on the National Register of Historic Places.