Bison is a rural unincorporated community located on US Highway 81 in Garfield County, Oklahoma, United States, consisting of a 30-acre town plat. The community was named for nearby Buffalo Springs. Buffalo Springs was a historic stage coach stop and a watering hole on the Chisholm Trail located about a mile north of Bison. Bison is home to a Catholic community, part of St. Joseph's parish under the Archdisocese of Oklahoma City. The church was erected in 1909, followed by a two-story brick school building operated by the Sisters of the Divine Providence from 1911 to 1934 when the Adorers of the Blood of Christ took over.