The Mary Murphy Mine was the principal gold mine of the Chalk Creek mining district of Chaffee County, Colorado, United States, near St. Elmo, Colorado. The Mary Murphy Mine operated continuously from 1870 to 1925, and produced 220 thousand ounces of gold, worth $4.4 million then (or about $180,000,000 in 2008), plus considerable silver, lead, and zinc. There were two aerial tramways connecting the mine to Romley, Colorado and the Denver, South Park and Pacific Railroad.