The Bill Williams River is a 46.3-mile-long (74.5 km) river in west-central Arizona where it, along with its tributary, the Santa Maria River, form the boundary between Mohave County to the north and La Paz County to the south. It is a major drainage westwards into the Colorado River of the Lower Colorado River Valley south of Hoover Dam and Lake Mead, and the drainage basin covers portions of northwest, and west-central Arizona. The equivalent drainage system paralleling the east–west lower reaches of the Bill Williams is the Gila River, which flows east-to-west across central Arizona, joining the Colorado River in the southwest at Yuma.