The Chilkoot River is a river in Southeast Alaska, United States, that extends about 20 miles (32 km) from its source and covers a watershed area of 100 square miles (260 km²). The source of the river is in the Takshanuk Mountains to the west and the Freebee glacier and unnamed mountains to the east. From its source, the upper reach of the river extends approximately 16 miles (26 km) to the point where it enters Chilkoot Lake.