South Padre Island is a resort town in Cameron County, Texas, United States. It is part of the Brownsville–Harlingen Metropolitan Statistical Area. It may be included as part of the Brownsville–Harlingen–Raymondville and the Matamoros–Brownsville metropolitan areas. The population was 2,816 at the 2010 census. The town is located on South Padre Island, a barrier island along the Texas Gulf Coast accessible via a causeway from the town of Port Isabel.