Great Tellico was a Cherokee town at the site of present-day Tellico Plains, Tennessee, where the Tellico River emerges from the Appalachian Mountains. Great Tellico was one of the largest Cherokee towns in the region, and had a sister town nearby named Chatuga. Its name in Cherokee is more properly written Talikwa. It is sometimes spelled Telliquo, Telliquah or, in Oklahoma, Tahlequah. There were several Cherokee settlements named Tellico, the largest of which is distinguished from the others by calling it "Great". The meaning of the word "Talikwa" is thought to be lost by the Cherokees.