Clarke University is a four-year liberal arts college located in Dubuque, Iowa, United States, affiliated with the Roman Catholic Church in the Archdiocese of Dubuque. The campus is situated on a bluff overlooking the Mississippi River and picturesque downtown Dubuque. Clarke is known regionally as the "College for the Arts", and offers a broad undergraduate curriculum in 19 academic departments with over 40 majors and programs.