Mole Lake, Wisconsin is an unincorporated census-designated place located in the town of Nashville in Forest County, Wisconsin, United States. The community is located on Wisconsin Highway 55 in the Mole Lake Indian Reservation. As of the 2010 census, its population is 435. Mole Lake has an area of 4.160 square miles (10.77 km²); 3.698 square miles (9.58 km²) of this is land, and 0.462 square miles (1.20 km²) is water. It is named after the Mole Lake tribe.