Callowhill is a neighborhood in Philadelphia, Pennsylvania, USA. It is roughly located in the vicinity of Callowhill Street, between Vine Street, Spring Garden Street, Broad Street, and 8th Street. It is named for Hannah Callowhill Penn, William Penn's second wife. Callowhill was formerly home to large-scale manufacturing and other industries, of which an architectural history has been left in the form of grand old abandoned factories. During the 1970s and 80s, the population of Callowhill plummeted, and although numbers are rising, it is a fairly unpopulated section of the city compared to surrounding neighborhoods.