Blue Ball is a town in the southwestern part of the U.S. state of Ohio that was established in 1820 at the intersection of the Dixie Highway (later U.S. Route 25). "The Blue Ball hung at the intersection of where the Historic Toddle Inn is located.... This was located just several hundred feet from what is said to be State Route 122." and what became State Route 122. It was originally called "Guilford" after Nathaniel Guilford, a prominent state politician at the time.