The Washington Run Railroad was a branch line connected to the B&O Railroad. Although primarily a freight carrier, it also had a passenger car, and ran a passenger service as well. It ran from Layton, Pennsylvania, crossed the Youghiogheny River on a bridge, then passed through a tunnel to continue to Perryopolis, Pennsylvania. From there, it continued to Star Junction, Pennsylvania, on a track that ran parallel to Pennsylvania Route 51. The line carried passengers and freight, including coke produced at Star Junction and coal for the Washington Coal and Coke Company and the Cochran Coal Company.