The Muscatatuck National Wildlife Refuge is a National Wildlife Refuge located three miles (5 km) east of Seymour, Indiana, on U.S. Route 50. Established in 1966, it comprises 7,802 acres (31.57 km²) in its main area of eastern Jackson and western Jennings counties, and an additional 78 acres (320,000 m²) in northwestern Monroe County, near Bloomington, Indiana, known as the "Restle Unit". It was established thanks to the selling of Federal Migratory Waterfowl Stamps, commonly known as Duck Stamps, by the United States Fish and Wildlife Service. It was Indiana's first National Wildlife Refuge.