Coxs Creek is an unincorporated community along U.S. Routes 31E/150 (known locally as Louisville Road) in Nelson County, Kentucky, United States, 4½ miles north of the county seat of Bardstown. It is named for Colonel Isaac Cox of Pennsylvania, who built a "fort" (actually an "old time block house") at the site in April 1775 before he fought in the American Revolutionary War, with the help of his brother James. The land had actually been his father's (David Cox), but David moved back to Virginia before he developed it. More of a station, Cox's 1,000 acres (4.0 km²) was said to be the first pioneer station in Nelson County.