Wilkes-Barre /ˈwɪlksbæri/ is a city in the State of Pennsylvania and the county seat of Luzerne County. It is one of the principal cities in the Scranton–Wilkes-Barre–Hazleton, PA Metropolitan Statistical Area. Located at the center of the Wyoming Valley it is second only to the nearby city of Scranton. The Scranton–Wilkes-Barre–Hazleton, PA Metropolitan Statistical Area had a population of 563,631 as of the 2010 Census making it the fourth largest metro/statistical area in the state of Pennsylvania. Wilkes-Barre and the surrounding Wyoming Valley are framed by the Pocono Mountains to the east, the Endless Mountains to the west and the Lehigh Valley to the south.