The Wami River lies entirely within the African nation of Tanzania in the Pwani Region and Morogoro Region in eastern Tanzania. Its source is specified in the Kaguru Mountains and it flows East entering the Indian Ocean west of Zanzibar. But its catchment area extends from the Kinyasangwe River to far beyond Dodoma to the southern edge of the Maasai Steppe and is denoted with 43,946 km². Only after leaving the Mkata River basin on the northern edge of the Mikumi National Park is its name Wami. Due to deforestation and climatic changes in the region the runoff decrease.