Usselo ['ʏsəloː] is a Dutch village in the municipality of Enschede in the eastern Netherlands in region of Twente. It is located just west of Enschede and east of Boekelo. It has existed for over 800 years. Archeology shows that the region was inhabited more or less continuously since the last ice-age. The region is very fertile and will support agriculture and cattle. The countryside is marked by artificial hills, called es or esch, which were formed by depositing dung mixed with dirt.