Tlalnelhuayocan is one of the 212 municipalities in the Mexican state of Veracruz, located 2 kilometres from state capital Xalapa-Enríquez. It stands on the Mexico City–Veracruz railway and on Federal Highways 180 and 125. Its name was San Andrés Tlalnelhuayocan, who is the first name was used to the Nahuatl and the people of Jilotepec.