La Santísima Church is located 12 La Santísima Street at corner of Emiliano Zapata Street in the historic center of Mexico City. Its full name is Temple and Hospital of the Most Holy Trinity (Templo y Antiguo Hospital de la Santisíma Trinidad) . The church was built between 1755 and 1783 as a temple for the adjoining hospital/hospice for priests. The hospital functioned until 1859, when the Reform Laws nationalized much of Church’s property in Mexico.