Santa Cruz de Juventino Rosas is a Mexican city (and municipality) located in the central east region of the state of Guanajuato. The municipality has an area of 428.64 square kilometres (1.40% of the surface of the state) and is bordered to the north by San Miguel de Allende, to the northeast by Comonfort, to the southeast by Celaya, to the south by Villagrán, and to the west by Salamanca.