St Luke's Church is in the village of Lower Whitley, in the civil parish of Whitley, Cheshire, England. The church is recorded in the National Heritage List for England as a designated Grade II* listed building. It is an active Anglican parish church in the diocese of Chester, the archdeaconry of Chester and the deanery of Great Budworth. It is one of three parish churches in the parish of Aston-by-Sutton, Little Leigh and Lower Whitley. The other two being St Peter, Aston-by-Sutton and St Michael and All Angels, Little Leigh.