St James' Church is in the village of Audlem in south Cheshire, England. It is recorded in the National Heritage List for England as a designated Grade I listed building. The church dates from the late 13th century with additions in the 19th century. It is an active Anglican parish church in the diocese of Chester, the archdeaconry of Macclesfield and the deanery of Nantwich. Its benefice is combined with those of St John, Doddington, and St Chad, Wybunbury.