The A52 is a major road in the East Midlands, England. It runs east from a junction with the A53 at Newcastle-under-Lyme near Stoke-on-Trent via Ashbourne, Derby, Stapleford, Nottingham, West Bridgford, Bingham, Grantham, Boston and Skegness to the east Lincolnshire coast at Mablethorpe.