Thame railway station was a station on the Wycombe Railway serving the town of Thame in Oxfordshire. It was opened in 1862 as the terminus of an extension from High Wycombe via Princes Risborough The cost of construction of the station building was £2201 1S 5d additional general works were £2137 8S 8d. In 1864 the line was extended from Thame to Oxford.