Cholmondeston is a village (at SJ628599) and civil parish in the unitary authority of Cheshire East and the ceremonial county of Cheshire, England. The village lies 5 miles to the north west of Nantwich. Nearby villages include Aston juxta Mondrum, Barbridge, Calveley and Wettenhall. The Middlewich branch of the Shropshire Union Canal and the Crewe–Chester railway line run through the civil parish. The area is predominantly rural, with a total population of around 150 in 2001.