The Bedford to Hitchin Line was a branch of the Midland Railway which served stations at Cardington, Southill, Shefford and Henlow Camp in Bedfordshire, England. It opened in 1857, but was largely made redundant as a through-route to London by the extension of the Midland Main Line to St Pancras. The last passenger train ran in December 1961, yet goods services lingered on until 1964.