Meskanena Mareko ("Meskane and Mareko") was one of the 77 woredas in the Southern Nations, Nationalities, and Peoples' Region of Ethiopia. Part of the Gurage Zone, Meskanena Mareko was bordered on the south by Silte, on the southwest by Gumer, on the west by Ezhana Wolene, on the northwest by Kokir Gedebano Gutazer, on the north by Sodo, and on the east by the Oromia Region. Towns in Meskanena Mareko included Butajira and Inseno.