The Missisquoi River is a tributary of Lake Champlain, approximately 80 mi (130 km) long, in northern Vermont in the United States and southern Quebec in Canada. It drains a rural area of the northern Green Mountains along the US-Canada border northeast of Lake Champlain, and an area of Quebec's Eastern Townships. The South Branch rises in Vermont and runs generally from southeast to northwest; the North Branch rises in Lake Eastman, Quebec, and runs from north to south. The North Branch and the South Branch join at Highwater, Quebec, just downriver from North Troy, Vermont.