Thốt Nốt is the main urban district of the city of Cần Thơ in the Mekong Delta region of Vietnam. To the south and west it borders Vĩnh Thạnh District and An Giang Province, and to the north with Đồng Tháp Province. As of 2003 the district had a population of 192,327. By 2007 this had risen to 196,610. The district covers an area of 171 km².