Lithia Springs Hotel was a grand hotel in Tallapoosa, Georgia built by Ralph L. Spencer between 1881 and 1882. It was the largest hotel in the Southeast in the late 19th century to early 20th century. It had 175 rooms, a banquet hall, an elevator, a billiard hall, poolrooms, and a large ballroom. People from all over the country traveled to the Lithia Springs Hotel for health reasons, business, or leisure travel. Many from New York traveled by train for 32 hours. The cost of a roundtrip ticket to Tallapoosa was $38.65. Unfortunately, the economy caused the grand hotel to shut its doors.