The Anaktuvuk River is a river in Alaska's North Slope. One hundred and thirty-five miles (217 km) long, it flows west from glaciers in the Endicott Mountains changing direction just north of Anaktuvuk Pass to flow north to the Arctic Coastal Plain where it joins the Colville River. Its headwaters are formed by runoff from various glaciers in the Gates of the Arctic Wilderness on the slopes of Fan Mountain, Alapah Mountain and Limestack Mountain, the last of which lies on the watershed divide between the Arctic Coastal Plain and the Koyukuk River, and feeds the Anaktuvuk River via Graylime Creek. Its first major tributary is the John River which joins it at (68°12′14″N151°36′50″W).