Maryland Route 17 (MD 17) is a state highway in the U.S. state of Maryland. The state highway begins at the Virginia state line at the Potomac River in Brunswick, where the highway continues south as Virginia State Route 287 (SR 287). MD 17 runs 29.49 miles (47.46 km) north from the Brunswick Bridge to the Frederick–Washington county line near Wolfsville. The state highway serves as the main north–south highway of the Middletown Valley of western Frederick County. MD 17 connects Brunswick and Wolfsville with Rosemont, Burkittsville, Middletown, and Myersville. The state highway also connects those communities with the valley's main east–west highways, which include U.S.