Srey Santhor District (Khmer: ស្រុកស្រីសន្ធរ; "Glorious City") is a district (srok) located in Kampong Cham Province, Cambodia. The district capital is Srey Santhor town located on the south bank of the Mekong River around midway between Phnom Penh and the provincial capital of Kampong Cham. There are no direct roads to the district and access is by boat and ferry, however a bridge is under construction.