Tsakalonisi (Greek: Τσακαλονήσι) is a small Greek island in the Ionian Sea, part of the Echinades archipelago. As of 2011, it had no resident population. It is situated 0.3 km west of Provati, 0.8 km southwest of Karlonisi, 1 km southeast of Drakonera, 4 km off the coast of Aetolia-Acarnania and 27 km east of Ithaca.