Wormleighton Manor is a manor house in the civil parish of Wormleighton in the historic county of Warwickshire, England. It belonged to the wealthy Spencer family during the 16th and 17th century. Much of the house was burned down by Royalists during the English Civil War in 1645 and abandoned by the Spencers in favour of Althorp, which contains some materials salvaged from Wormleighton to this day.