Goncha Siso Enese is one of the woredas in the Amhara Region of Ethiopia. Part of the Misraq Gojjam Zone, Goncha Siso Enese is bordered on the south by Enarj Enawga, on the west by Hulet Ej Enese, on the north by the Abay River which separates it from the Debub Gondar Zone, and on the east by Enbise Sar Midir.