La'ilay Adiyabo (Tigrinya "Upper Adiyabo") is one of the woredas in the Tigray Region of Ethiopia. Part of the Semien Mi'irabawi Zone, La'ilay Adiyabo is bordered on the south by Tahtay Koraro, on the southwest by Asigede Tsimbela, on the northwest by Tahtay Adiyabo, on the northeast by the Mareb River which separates it from Eritrea, on the east by the Mehakelegnaw (Central) Zone, and on the southeast by Medebay Zana.