Portland Inlet is an inlet of the Pacific Ocean on the coast of British Columbia, Canada, approximately 55 kilometers north of Prince Rupert, British Columbia. It joins the Chatham Sound opposite the Dixon Entrance. It is 40 kilometers long and as much as 13 kilometers wide. It drains the Portland Canal, Nass River, and Khutzeymateen Inlet, among others, and is the site of Pearse Island and Somerville Island.