Port Macquarie is a town in the local government area of Port Macquarie-Hastings. It is located on the Mid North Coast of New South Wales, Australia, about 390 km (242 mi) north of Sydney, and 570 km (354 mi) south of Brisbane. The town is located on the coast, at the mouth of the Hastings River, and at the eastern end of the Oxley Highway (B56).