Webb County is a county located in the U.S. state of Texas. As of the official 2010 census population for the county is 250,304. Its county seat is Laredo. The county was named after James Webb, who served as Secretary of the Treasury, Secretary of State, and Attorney General of the Republic of Texas, and later judge of the United States District Court following the admission of Texas to statehood. By area, Webb County is the largest county in South Texas and one of the largest in the state.