The Warm Springs River is a river in north-central Oregon in the United States. It drains the east side of the Cascade Range and is a tributary to the Deschutes River. The watershed is approximately between Mount Jefferson and Timothy Lake, and the northwestern and southwestern boundaries of the Warm Springs Indian Reservation coincide with the watershed. The headwaters are less than ¹⁄₄ mile (0.40 km) from the Wasco County–Clackamas County boundary (which follows the Cascade crest). The river flows generally eastward, with occasional diagonals southeast or northeast.