Venice is an unincorporated community and census-designated place in Plaquemines Parish, Louisiana, United States. As of the 2010 census, its population was 202. It is 77 miles south of New Orleans on the west bank of the Mississippi River at (29°16′37″N89°21′17″W). It is the last community down the Mississippi accessible by automobile, and it is the southern terminus of the Great River Road.