Tepotzotlán (Spanish  [tepotsotla'n] ) is a city and a municipality in the Mexico state of Mexico. It is located 40 km northeast of Mexico City about a 45-minute drive along the Mexico City-Querétaro at marker number 41. In Aztec times, the area was the center of a dominion that negotiated to keep most of its independence in return with being allied with the Aztec Triple Alliance. Later, it would also be part of a “Republic of the Indians,” allowing for some autonomy under Spanish rule as well. The town became a major educational center during the colonial period when the Jesuits established the College of San Francisco Javier.