St. Margaret Lothbury is a Church of England parish church in the City of London; it spans the boundary between Coleman Street Ward and Broad Street Ward. Recorded since the 12th century, the church was destroyed in the Great Fire of London in 1666 and rebuilt by the office of Sir Christopher Wren. St. Margaret Lothbury still serves as a parish church, as well as being the official church of five Livery Companies, two Ward Clubs and two Professional Institutes.